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. Author manuscript; available in PMC: 2010 Jan 7.
Published in final edited form as: Nature. 2009 Jun 3;459(7249):996–999. doi: 10.1038/nature08119

Figure 2.

Figure 2

Nox/Duox activity is required for wound margin H2O2 production and leukocyte recruitment. (a) Scheme of mammalian NADPH oxidases also found in zebrafish12,13. (b) Wound margin [H2O2] ± DPI or VAS2870 (VAS), or carrier (1% DMSO) imaged 17 min pw. (c) Statistical quantification of wound margin [H2O2]. (d) Injured tail fins of mpo::GFP9 larvae ± DPI (42 min pw). Coloured lines: leukocyte tracks derived from the corresponding time-lapse movies. (e) Statistical quantification of leukocyte recruitment to wound margin. Error bars: SEM of indicated number of larvae (brackets). *** P < 0.001 (vs. control). Scale bars: 100 μm.