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Infection with Ad-AKAP150-siRNA but not Ad-Luc-siRNA caused a decrease in the spontaneous Ca2+ oscillations. Spontaneous Ca2+ oscillations (A) and the interpulse interval (IPI; B) between the spontaneous Ca2+ oscillations in uninfected GT1-1 cells (n = 132) or GT1-1 cells infected with 5 MOI of Ad-Luc-siRNA (n = 125) or 5 MOI of Ad-AKAP150-siRNA (n = 134). Data are the mean ± sem from three separate experiments. ***, P < 0.0001 relative to uninfected and Ad-Luc-siRNA infected cells.
