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Box plot analysis illustrating levels of mtDNA in peripheral blood of breast cancer patients according the menopausal status. The quantitative mtDNA content is shown on the Y axis. The mtDNA content in peripheral blood of postmenopausal patients is significant lower than premenopausal patients according the Mann-Whitney U Test (* P = 0.024, NS: not significant); Horizontal lines: group medians; boxes: 25--75% quartiles, range, peak and minimum.
