TABLE 3.

Pearson correlation coefficients of the lipid profile components with age, age at diagnosis, age at death, and average ability score for NPC1 patients

	Total Cholesterol	HDL Cholesterol	LDL Cholesterol	Triglycerides
Age (years)	NS	NS	0.41b(N = 28)	NS
Age at diagnosis	NS	NS	NS	NS
Age at death	NS	0.96c(N = 5)	NS	NS
Average ability scorea	NS	NS	−0.35d(N = 34)	NS

^aThe average ability score was computed by taking the mean of the four individual abilities as assessed on the questionnaire. These abilities included walking, movement, language, and swallowing. Each of the individual abilities were ranked from 1 to 4, or 1 to 5, with a score of “1” being normal and scores of “4” or “5” being the most severe level of disability. NS = Not significant.

^b P = 0.032.

^c P = 0.011.

^d P = 0.045.