TABLE 1.
Baseline characteristics of cases and matched controls
| Cases | Controls | P | |
|---|---|---|---|
| Study population, n | 933 | 1,852 | – |
| Demographic and lifestyle parameters | |||
| Age (years) | 65.4 (7.7) | 65.4 (7.7) | Matched |
| Women, % (n) | 35.9 (335) | 37.3 (691) | Matched |
| BMI (kg/m2) | 27.3 (3.9) | 26.2 (3.4) | <0.001 |
| Diabetes, % (n) | 6.8 (63) | 1.8 (33) | <0.001 |
| Smokers, % (n) | 15.1 (141) | 8.4 (166) | <0.001 |
| Alcohol use, units per week* | 2.5 (0.5-8.0) | 4.0 (1.0-10) | 0.001 |
| Systolic blood pressure (mmHg) | 143.6 (18.8) | 138.9 (17.9) | <0.001 |
| Diastolic blood pressure (mmHg) | 85.8 (12.1) | 84.4 (11.5) | <0.001 |
| Lipids and lipoproteins | |||
| Total cholesterol (mmol/l) | 6.45 (1.2) | 6.26 (1.1) | <0.001 |
| Triglycerides (mmol/l)* | 1.9 (1.40-2.80) | 1.6 (1.20-2.30) | <0.0001 |
| LDL-C (mmol/l) | 4.27 (1.1) | 4.08 (1.0) | <0.001 |
| HDL-C (mmol/l) | 1.26 (0.37) | 1.37 (0.40) | <0.001 |
| apoA-I (mg/dl) | 155.1 (29.5) | 162.2 (28.7) | <0.01 |
| apoB (mg/dl) | 136.6 (31.7) | 128.4 (29.9) | <0.001 |
| LCAT (μg/ml) | 8.89 (2.10) | 8.91 (2.25) | 0.78 |
Controls were matched to cases for age, sex, and enrolment time. Data are presented as mean values with SD in parentheses or as a percentage of the total group. P values are for one-way ANOVA on continuous variables or for χ2 analysis on categorical variables. *Mean and interquartile range. Because of skewed distribution, data on alcohol and triglycerides were log-transformed prior to performing a one-way ANOVA test.