TABLE 1.
Demographic and biochemical characteristics of THS participants by gender (samples collected between 1990–1995 and 2000–2003)
| 1990–1995 Cohort |
2000–2003 Cohort |
|||||
|---|---|---|---|---|---|---|
| Males(n = 1549) | Females(n = 1063) | P | Males(n = 474) | Females(n = 690) | P | |
| Age (years) | 42.1 ± 13.2 | 42.2 ± 14.9 | NS | 44.1 ± 13.1 | 44.4 ± 13.9 | NS |
| BMI (kg/m2) | 26.1 ± 3.9 | 26.6 ± 5.4 | <0.05 | 28.1 ± 3.8 | 29.9 ± 5.4 | <0.05 |
| HDL-C (mg/dl) | 35.7 ± 7.5 | 41.2 ± 9 | <0.001 | 38.7 ± 8.5 | 47.0 ± 9.4 | <0.001 |
| Total cholesterol (mg/dl) | 183 ± 44 | 183 ± 42 | NS | 182 ± 37 | 184 ± 43 | NS |
| Total cholesterol/HDL-C ratio | 5.8 ± 2.9 | 4.5 ± 1.4 | <0.01 | 5.0 ± 1.6 | 4.0 ± 1.9 | <0.01 |
| LDL-C (mg/dl) | 126 ± 41 | 116 ± 39 | <0.05 | 112 ± 33 | 113 ± 35 | NS |
| Triglycerides (mg/dl) | 153 ± 107 | 110 ± 70 | <0.001 | 155 ± 105 | 118 ± 67 | <0.001 |
| Systolic blood pressure (mm Hg) | 125 ± 23 | 122 ± 21 | NS | 132 ± 20 | 133 ± 22 | NS |
| Diastolic blood pressure (mm Hg) | 82 ± 14 | 81 ± 13 | NS | 84 ± 12 | 85 ± 13 | NS |
| Consumption of alcohol (%)a | 29.8 | 5.6 | <0.001 | 36.7 | 9.6 | <0.001 |
| Cigarette smoking (%)b | 56.6 | 24 | <0.001 | 67.2 | 25.2 | <0.001 |
Values shown are means ± SD or percentages. Means were compared by t-test, and percentages were analyzed by chi-square test. NS, not significant.
a
One or more drinks per week.
b
One or more cigarettes per day.