Table 5.
Top 30 over-expressed protein-coding genes in MSC from UCB
| Overexpressed in UC | |||||
|---|---|---|---|---|---|
| Entrez Gene ID | Gene Symbol | Mapping.location | Description | SAM q-value (%) | Fold Change |
| 84302 | C9orf125 | 9q31.1 | chromosome 9 open reading frame 125 | 0 | 51.5 |
| 81578 | COL21A1 | 6p12.3-p11.2 | collagen, type XXI, alpha 1 | 0 | 40.0 |
| 3679 | ITGA7 | 12q13 | integrin, alpha 7 | 0 | 28.1 |
| 79614 | C5orf23 | 5p13.3 | chromosome 5 open reading frame 23 | 0 | 25.7 |
| 2044 | EPHA5 | 4q13.1 | EPH receptor A5 | 0 | 25.0 |
| 2006 | ELN | 7q11.23 | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 0 | 23.9 |
| 7373 | COL14A1 | 8q23 | collagen, type XIV, alpha 1 (undulin) | 0 | 23.9 |
| 10631 | POSTN | 13q13.3 | periostin, osteoblast specific factor | 0 | 22.3 |
| 5168 | ENPP2 | 8q24.1 | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 0 | 16.7 |
| 5137 | PDE1C | 7p15.1-p14.3 | phosphodiesterase 1C, calmodulin-dependent 70kDa | 0 | 15.3 |
| 8839 | WISP2 | 20q12-q13.1 | WNT1 inducible signaling pathway protein 2 | 0 | 15.2 |
| 183 | AGT | 1q42-q43 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0 | 14.4 |
| 8490 | RGS5 | 1q23.1 | regulator of G-protein signalling 5 | 0 | 13.9 |
| 182 | JAG1 | 20p12.1-p11.23 | jagged 1 (Alagille syndrome) | 0 | 13.1 |
| 1879 | EBF1 | 5q34 | early B-cell factor 1 | 0 | 12.5 |
| 253738 | EBF3 | 10q26.3 | early B-cell factor 3 | 0 | 12.3 |
| 2012 | EMP1 | 12p12.3 | epithelial membrane protein 1 | 0 | 11.7 |
| 6696 | SPP1 | 4q21-q25 | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 0 | 10.9 |
| 23136 | EPB41L3 | 18p11.32 | erythrocyte membrane protein band 4.1-like 3 | 0 | 10.7 |
| 3983 | ABLIM1 | 10q25 | actin binding LIM protein 1 | 0 | 10.5 |
| 3783 | KCNN4 | 19q13.2 | potassium intermediate/small conductance calciumactivated channel, subfamily N, member 4 | 0 | 10.2 |
| 342184 | FMN1 | 15q13.3 | formin 1 | 0 | 10.1 |
| 5328 | PLAU | 10q24 | plasminogen activator, urokinase | 0 | 9.2 |
| 130916 | MTERFD2 | 2q37.3 | MTERF domain containing 2 | 0 | 8.6 |
| 9510 | ADAMTS1 | 21q21.2 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0 | 8.5 |
| 9783 | RIMS3 | 1pter-p22.2 | regulating synaptic membrane exocytosis 3 | 0 | 7.9 |
| 57520 | HECW2 | 2q32.3-q33.1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | 0 | 7.9 |
| 4629 | MYH11 | 16p13.11 | myosin, heavy chain 11, smooth muscle | 0 | 7.8 |
| 255488 | IBRDC2 | 6p22.3 | IBR domain containing 2 | 0 | 6.8 |