Table 1.
Clinical and demographic characteristics of the subjects
GAD Elderly Subjects (group A) (N=134) | Comparison Elderly Subjects (group B) (N=33) | GAD General Adult Subjects (group C) (N=186) | t Test (1)/chi Square (2) | One way ANOVA (F-test) | df | p value | Pairwise comparison (Tukey post-hoc test) | |
---|---|---|---|---|---|---|---|---|
Demographic | ||||||||
Age – Mean (SD) | 72.1 (8.0) | 74.3 (6.2) | 43.4 (10.4) | 439.98 | 2,350 | 0.0001 | C<B, A | |
%Men | 35% | 33% | 27% | 2.59 | 2 | 0.27 | ||
%White | 81% | 100% | 83% | 7.10(2) | 2 | |||
Other Anxiety disorders N (%) | 50 (37%) | - | 103 (55%) | |||||
Education - Mean (SD) | 13.8 years (3.0) | 14.2 years (2.9) | 80% ≥ 12th grade | # | # | # | # | |
Clinical measures – Mean (SD) | ||||||||
GADSS | 12.4 (3.1) | 1.6 (2.1) | 15.3 (3.4) | 260.21 | 2,350 | 0.0001 | A≠B≠C | |
HRSA | 23.0 (4.7) | 5.1 (3.9) | 28.6 (6.8) | 230.78 | 2,350 | 0.0001 | A≠B≠C | |
PHQ9 | * | * | 13.5 (5.3) | |||||
HRSD | 12.2 (4.1) | 1.8 (2.1) | ** | 14.18 (1) | 165 | 0.0001 | ||
MMSE | 28.1 (2.0) | 29.0 (1.3) | ** | 2.22 (1) | 160 | 0.028 | ||
PSWQ | 57.4 (12.2) | 29.0 (7.6) | ** | 11.90 (1) | 159 | 0.0001 | ||
CIRS | 9.1 (3.9) | 9.3 (3.1) | 1.13 (1) | 160 | 0.26 | |||
MOS MCS | 40.8 (8.8) | 59.4 (3.7) | 28.3 (11.0) | 168.12 | 2,348 | 0.0001 | A<B<C | |
MOS PCS | 41.1 (11.3) | 47.5 (7.2) | 46.6 (11.8) | 10.38 | 2,348 | 0.0001 | A<B, C |
GADSS= Generalized Anxiety Disorder Severity Scale; HRSA= Hamilton Rating Scale for Anxiety; PHQ9= Patient Health Questionnaire, 9-item depression scale; HRSD= Hamilton Rating Scale for Depression; MMSE=Mini Mental State Examination; PSWQ=Penn State Worry Questionnaire; CIRS-G=Cumulative Illness Rating Scale for Geriatrics; MOS MCS= Medical Outcome Stud, mental component scale; MOS PCS= Medical Outcome Study, physical component scale; df= degrees of freedom;
not compared due to different scales used for assessment;
measure unavailable for the elderly subjects;
measure unavailable for the younger subjects.