Figure 2.
A. Anti-CCP antibodies in sera from patients with SLE (total 329), RA (n = 49), and healthy controls (NHS; n = 35) were tested by ELISA. Six additional Japanese SLE patients with deforming/destructive arthropathy were included. OD were converted into units. Cutoff value of anti-CCP and anti-CAP is 1.7 units (shaded area). B. Anti-CCP/anti-CAP ratios in anti-CCP-positive sera (> 1.7 units) from SLE or RA cases or healthy controls (NHS). Data for 4 Japanese patients are shown. The ratios were high (> 2.0) in 91% of RA with anti-CCP, but was high only in SLE cases with deforming/destructive arthritis or a case with joint swelling not fulfilling RA criteria. Cutoff value of anti-CCP/anti-CAP ratio is 2.0 (shaded area).