Table 4.
Interaction of ERCC1 and XRCC1 polymorphisms on survival of lung adenocarcinoma
ERCC1 CC | ERCC1 CT/TT | |||
---|---|---|---|---|
XRCC1 | MST | HR(95%CI)A | MST | HR(95%CI)A |
GG | 25.10 | 1.00 | 13.30 | 1.79(1.16-2.76) |
GA/AA | 12.47 | 1.64(1.11-2.44) | 8.60 | 2.44(1.63-3.65) |
Abbreviation: MST, median survival time; HR, hazard ratio; CI, confidence interval.
AHR and 95%CI were calculated by Cox regression, with the ERCC1 wild genotype (CC) and XRCC1 wild genotype (GG) as the reference group;HRs were adjusted for age, stage, surgical operation and chemotherapy or radiotherapy.