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. 2010 Jan;82(1):55–59. doi: 10.4269/ajtmh.2010.09-0219

Table 2.

Treatment and follow-up of newborns with congenital T. cruzi infection diagnosed at the time of birth or within 30 days of age, Hospital Regional Ushuaia, Ushuaia, 2001–2002

Variable Case 1 Case 2 Case 3
Age of diagnosis 10 days 2 days 10 hours
IHA before treatment 1/512 1/512 1/128
EIA (IP) before treatment 5.3 6.6 4.7
EIA-SAPA cut-off = 0.300 DO = 1.885 reactive DO = 1.118 reactive DO = 2.607 reactive
Clinical manifestation No No No
Age when treatment started 21 days 9 days 2 days
Tolerance of treatment Good (no adverse events) Good (no adverse events) Good (no adverse events)
Age at first control post-treatment 9 months 10 months 8 months
IHA at first control post-treatment Not reactive Not reactive Not reactive
EIA (IP) at first control post-tratment 1.0 1.0 Not reactive
EIA-SAPA at first control post-treatment DO = 0.319 (low reactive) DO = 0.188 (not reactive) DO = 0.132 (not reactive)
Age at second control post-treatment 4 years old 4 years old 17 months
IHA at second control post-treatment Not reactive Not reactive Not reactive
EIA (IP) at second control post-treatment Not reactive Not reactive Not reactive
EIA-SAPA at second control post-treatment DO = 0.164 (not reactive) DO = 0.132 (not reactive) DO = 0.106 (not reactive)

IP = index of positivity (OD/cut-off); IHA = indirect hemagglutination; EIA = enzyme-linked immunosorbent assay.