TABLE 1.

Subunit composition of the archaeal RNase P and the eukaryal nuclear RNase P and RNase MRP

Yeast RNase P/RNase MRP (S. cerevisiae)1					Mammalian RNase P/RNase MRP (H. sapiens)2					Archaeal RNase P (P. horokoshii)3
	Properties		Subunit			Properties		Subunit		Subunit	Properties
Gene	Mr	(pI)	P	MRP	Gene	${\text{M}}_{\text{r}}^{\#}$	(pI)	P	MRP	P	Mr	(pI)
RNA					RNA					RNA
RPR1	120		(+)		H1	112		(+)		PH rnpB*	107
NME1	112			(+)	7–2	88			(+)
Protein					Protein					Protein
POP1	100.5	9.8	(+)	(+)	hPOP1	115	9.6	(+)	(+)
POP3	22.6	9.6	(+)	(+)	RPP38	38	9.6	(+)	(+)
POP4	32.9	9.3	(+)	(+)	RPP29	29	10.2	(+)	(+)	PH1771	15.1	11.2
POP5	19.6	7.8	(+)	(+)	hPOP5	19	7.9	(+)	(+)	PH1481	14.0	10.0
POP6	18.2	9.3	(+)	(+)
POP7	15.8	9.3	(+)	(+)	RPP20	20	8.6	(+)	(+)
POP8	15.5	4.6	(+)	(+)
RPP1	32.2	9.8	(+)	(+)	RPP30	30	9.2	(+)	(+)	PH1877	24.7	9.6
RPR2	16.3	10.0	(+)		RPP21	21	9.6	(+)		PH1601	14.6	10.5
SNM1	22.5	9.8		(+)
RMP1	23.6	9.8		(+)
					RPP40	40	5.2	(+)
					RPP25	25	9.7	(+)	(+)
					RPP14	14	7.6	(+)

¹Data from (Xiao et al., 2002).

²Data from (Jarrous, 2002).

³Data obtained from UniProtKB/Swiss-Prot (http://us.expasy.org/sprot/).

^*The P. horikoshii RNase P RNA gene has not been annotated.

^#Molecular weights are based upon gel migrations in many cases the mass differs from that calculated from the sequence.