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. 2009 May 28;20(2):315–327. doi: 10.1093/cercor/bhp101

Table 3.

Predicted other effects

a) Irregular > regular (whole-brain analysis) Over groups
British group
Italian group
x,y,z Z V001 x, y, z Z V001 x, y, z Z V001
Left pars orbitalis −38, 32, −6 5.0 119 −40, 32, −6 3.5 8 −36, 30, −4 5.0 93
−38, 44, −10 3.1 −38, 44, −10 2.3 −50, 38, −12 3.8
−48, 36, −12 3.1 −48, 34, −14 1.6 −40, 40, −14 3.0
Left anterior O.T.s (ROI = −42 −42 −18) −46, −48, −16 3.5 32 −40, −46, −12 4.9 136 −42 −38 −14 2.0 0
b) Pseudoword reading Over groups British group Italian group
x, y,z Z V001 x, y, z Z V001 x, y,z Z V001
Left dorsal premotor cortex (ROI = −56 0 40) −46, 0, 32 5.6 426 −52, 6, 36 4.1 237 −46, 0, 34 4.0 177
−50, 4, 40 4.0 −48, −2, 44 2.3 −50, 0, 40 3.3
Left posterior O.T.s. (ROI = −46 −60 −18) −50, −60, −18 4.3 51 −52, −60, −18 4.1 22 −46, −58, −14 3.6 7
c) Processing load Over groups British group Italian group
x,y, z Z V001 x, y, z Z V001 x, y, z Z V05
Left pars opercularis (ROI = −54 8 18) −60, 12, 14 4.3 41 −60, 12, 14 4.2 22 −50, 8, 14 3.1 254
Left mid O.T.s (ROI = −46 −54 −18) −44, −52, −12 4.1 51 −44, −54, −12 4.4 22 −46, −54, −16 2.5 90
Right cerebellum 28, −64, −32 4.8 159 28, −64, −32 3.8 24 32, −60, −30 3.6 44
Left putamen −24, 2, −2 4.9 135 −24, 2, −2 4.9 91 −24, 0, 2 2.1 7
d) Second > first language (whole-brain analysis) Over groups British group Italian group
x,y, z Z V001 x, y,z Z V001 x, y, z Z V001
Left dorsal premotor cortex −48, 2, 34 5.6 865 −44, 2, 30 4.5 245 −48, 0, 36 4.8 77
−50, 0, 40 4.3 52, 2, 40 3.5 −50, 0, 40 3.3
Left pars opercularis −56, 10, 10 5.5 −56, 10, 10 4.3 84 −56, 10, 10 3.6 41
−56, 8, 20 5.1 −56, 8, 20 3.7 −60, 6, 28 4.3
Right cerebellum 34, −68, −30 5.2 139 32, −60, −30 3.9 7 32, −58, −34 4.3 73

Note: Anatomical location (in MNI co-ordinates) and Z score (Z) for (a) reading irregular > regular words (i.e., activation for English words with irregular spellings relative to English words with regular spellings; (b) pseudowords reading (i.e., activation for pseudowords relative to first language words; and (c) Processing load (i.e., activation for pseudowords and irregularly spelled English words relative to regularly spelled English words); and (d) second > first language (i.e., Italian > English in English subjects and English > Italian in Italian subjects). V001 = Number of voxels at P < 0.001 uncorrected. V05 = Number of voxels at P < 0.05 uncorrected. Z scores greater than 3.0 are significant at P < 0.001; Z scores greater than 1.64 are significant at P < 0.05. Z scores and voxel counts in bold are those that were significant after correction for multiple comparisons across the whole brain for height (Z > 4.8) or extent (>90 voxels at P < 0.001). P > 0.05 uncorr = not significant even when threshold is lowered to P < 0.05 uncorrected.