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. Author manuscript; available in PMC: 2010 Jan 9.
Published in final edited form as: Muscle Nerve. 2009 Apr;39(4):503–511. doi: 10.1002/mus.21255

Figure 2. Contraction-induced p70S6k (Thr 389 & Thr 421/Ser 424) phosphorylation is altered with insulin resistance.

Figure 2

The basal (control) and contraction-induced phosphorylation of p70S6k in TA muscles from lean and obese Zucker rats at 0, 1, and 3 hours after contractile stimulus. p70S6k (Thr 389 & Thr 421/ser 424) phosphorylation was determined by Western blot analysis and immunodetection for phosphorylation on Thr389 andThr421/Ser424. All the protein quantifications were done after normalization by the abundance of β-tubulin protein. An asterisk (*) indicates a significant difference (P < 0.05) from the control within-animal model, and a cross (†) indicates significant difference (P < 0.05) at corresponding time points across animal models.