Table 2.
Comparison of resistance patterns between Shigella flexneri and Shigella sonnei isolated in southern Vietnam between 1995 and 2008.
| Collection | Serotype (n) | Phenotypeb | AMP | CHL | SXT | TET | NAL | OFX | CRO |
|---|---|---|---|---|---|---|---|---|---|
| A (1995 - 1996) | sonnei (24) | R | 11 | 8 | 23 | 23 | 0 | 0 | 0 |
| S | 13 | 16 | 1 | 1 | 24 | 24 | 24 | ||
| flexneri (56) | R | 54 | 10 | 53 | 53 | 9 | 0 | 0 | |
| S | 2 | 46 | 3 | 3 | 47 | 56 | 56 | ||
| p Valuea | < 0.0001 | 0.1287 | 0.8102 | 0.8102 | 0.0371 | - | - | ||
| B (2000 - 2002) | sonnei (54) | R | 50 | 10 | 53 | 52 | 9 | 0 | 1 |
| S | 4 | 44 | 1 | 2 | 45 | 54 | 53 | ||
| flexneri (50) | R | 46 | 38 | 44 | 49 | 21 | 0 | 0 | |
| S | 4 | 12 | 6 | 1 | 29 | 50 | 50 | ||
| p Valuea | 0.9316 | < 0.0001 | 0.0415 | 0.5577 | 0.0052 | - | 0.329 | ||
| C (2007 - 2008) | sonnei (71) | R | 17 | 5 | 71 | 69 | 51 | 0 | 12 |
| S | 54 | 66 | 0 | 2 | 20 | 71 | 59 | ||
| flexneri (30) | R | 25 | 28 | 28 | 30 | 19 | 1 | 1 | |
| S | 5 | 2 | 2 | 0 | 11 | 29 | 29 | ||
| p Valuea | < 0.0001 | < 0.0001 | < 0.0001 | 0.3696 | 0.4619 | 0.297 | 0.076 | ||
| Combined | sonnei (148) | R | 78 | 23 | 147 | 144 | 60 | 0 | 13 |
| S | 70 | 125 | 1 | 4 | 88 | 148 | 135 | ||
| flexneri (136) | R | 125 | 76 | 125 | 132 | 49 | 1 | 1 | |
| S | 11 | 60 | 11 | 4 | 87 | 135 | 135 | ||
| p Valuea | < 0.0001 | < 0.0001 | 0.001 | 0.613 | 0.365 | 0.478 | 0.002 | ||
a p Value calculated using the chi-squared test
b Phenotype with respect to Resistant (R) or Sensitive (S)
AMP; Ampicillin, CHL; Chloramphenicol, SXT; Trimethoprim- Sulfamethoxazole, TET; Tetracycline, NAL; Nalidixic Acid, OFX; Ofloxacin, CRO; Ceftriaxone.