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FAAH–MAP42c structure in blue and FAAH–5 structure in green. The distortion in residues 275–278 shown on the right and minor changes to Thr488, Phe432, and Phe381 shown on the left. The opened ABP not present with 1–4 is shown in surface representation on the right panel. 2Fo-Fc electron density maps at a contour level of 1.0σ for compound 5 are shown with white meshes.
