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The cocrystal structures of FAAH–5 (in green) and FAAH–243 (in yellow) display the difference in water H-bonds between an oxadiazole and oxazole core. 2Fo-Fc electron density maps at a contour level of 1.0σ and 1.5σ for compounds 5 and 243 with their water molecules, respectively, are shown with white meshes.
