Table 5.
Baseline and Change Scores on the Specific IBS Symptom Variables by Treatment Group
| Variable | Baseline | N | 3-Months | N | 6-Months | N | 12-Months | P value |
|---|---|---|---|---|---|---|---|---|
| Abdominal pain/discomfort | ||||||||
| UC | 35.2 (26.3) | 39 | −0.9 (22.8) | 40 | −1.9 ( 25.8) | 41 | −5.2 (16.6) | <.001 |
| CSM-T/IP | 35.1 (26.5) | 40 | −19.3 (27.2) | 36 | −20.4 (28.3) | 37 | −24.7 (24.6) | |
| CSM-IP | 45.3 (24.4) | 45 | −23.5 (23.0) | 44 | −20.8 (22.9) | 43 | −18.3 (27.0) | |
| Pair-wise p values b | .001, <.001, .631 | .003, .005, .708 | <.001, .026, .107 | |||||
| Bloating | ||||||||
| UC | 36.3 (29.7) | 36 | −7.3 (22.7) | 36 | −12.32 (24.2) | 38 | −10.89 (25.9) | .162 |
| CSM-T/IP | 41.3 (35.3) | 34 | −24.2 (31.6) | 31 | −23.92 (32.4) | 32 | −29.73 (25.9) | |
| CSM-IP | 37.2 (29.8) | 38 | −17.7 (27.9) | 38 | −12.65 (30.3) | 37 | −15.50 (29.4) | |
| Pair-wise p values b | .059, .092, .771 | .371, .932, .321 | .024, .522, .092 | |||||
| Constipation | ||||||||
| UC | 20.0 (23.0) | 24 | −11.2 (19.3) | 24 | −11.5 (21.7) | 26 | −10.7 (21.1) | .059 |
| CSM-T/IP | 22.0 (25.2) | 29 | −22.8 (24.8) | 26 | −21.8 (29.4) | 28 | −21.0 (32.5) | |
| CSM-IP | 25.4 (26.3) | 30 | −17.3 (19.4) | 29 | −12.6 (19.3) | 29 | −13.5 (21.5) | |
| Pair-wise p values b | .037, .270, .278 | .130, .896, .142 | .210,.928, .226 | |||||
| Diarrhea | ||||||||
| UC | 14.57 (18.81) | 22 | −4.20 (20.07) | 22 | −9.26 (17.46) | 24 | −10.19 (16.57) | .624 |
| CSM-T/IP | 17.23 (22.84) | 21 | −10.15 (23.93) | 19 | −11.38 (31.82) | 20 | −20.95 (21.92) | |
| CSM-IP | 15.36 (20.30) | 21 | −12.26 (18.18) | 22 | −15.08 (18.11) | 18 | −14.69 (18.25) | |
| Pair-wise p values b | .860, .165, .233 | .244, .917, .256 | .317, .938, .360 | |||||
| Intestinal gas | ||||||||
| UC | 41.84 (29.00) | 38 | −7.03 (26.75) | 39 | −9.61 (30.32) | 40 | −9.39 (27.58) | .006 |
| CSM-T/IP | 38.50 (32.11) | 40 | −20.44 (28.55) | 38 | −20.40 (28.44) | 39 | −23.58 (28.13) | |
| CSM-IP | 51.92 (29.33) | 45 | −25.71 (29.06) | 45 | −23.44 (26.65) | 44 | −24.22 (27.11) | |
| Pair-wise p values b | .009, .002, .713 | .049, .059, .876 | .009, .028, .633 | |||||
| Urgency | ||||||||
| UC | 20.03 (23.72) | 27 | −5.27 (18.99) | 29 | −7.07 (21.62) | 26 | −15.58 (22.68) | .143 |
| CSM-T/IP | 20.15 (23.33) | 26 | −12.46 (21.46) | 24 | −15.93 (23.95) | 23 | −25.84 (21.54) | |
| CSM-IP | 21.26 (23.76) | 24 | −19.20 (27.55) | 26 | −20.57 (17.04) | 25 | −17.82 (26.18) | |
| Pair-wise p values b | .255, .051, .393 | .204, .066, .584 | .075, .919, .097 | |||||
Note. CSM-T/IP = Comprehensive Self-Management-Telephone. CSM-IP = Comprehensive Self-Management-In-Person.
Symptom severity is reported as the percent of days with moderate or higher severity. Analyses for each symptom were restricted to only those subjects who rate that symptom as moderate or higher severity on at least 10 % of days at baseline.
a
P-value from Mixed methods for testing the null hypothesis that the mean is the same in all three treatment groups at all three time points, adjusting for the baseline value of the variable.
b
Pair-wise comparisons: CSM-T/IP vs. UC; CSM-IP vs. UC; CSM-T/IP vs. CSM-IP.