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AMPK β1−/− mice have reduced body mass and food intake. A, body mass of wild type and AMPK β1−/− mice fed a control chow or HFD at 22 and 29 weeks of age, respectively. B, reduced epidydymal white adipose tissue in AMPK β1−/− mice. C, average daily food intake in β1−/− mice fed a control chow or HFD. *, p < 0.05, and ***, p < 0.001 compared with wild type; #, p < 0.05 relative to chow.
