Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Oct 29;285(1):197–205. doi: 10.1074/jbc.M109.039677

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 7. — gp96 siRNA suppresses processing of ADAMTS9 Pro-Cat. A, gp96 siRNA suppresses the expression level of cellular gp96 (left panel). Transfection with gp96 siRNA does not significantly affect the total cellular levels of Pro-Cat (center panel) but decreases furin levels (right panel). B, expression of gp96 siRNA decreases levels of processed catalytic domain in conditioned medium (left panel) and the amounts of ADAMTS9 zymogen (center panel) and furin (right panel) at the cell surface. C, quantitation of cell-surface Pro-Cat and furin in gp96 siRNA-treated cells is expressed as a percentage of control siRNA-treated cells. Data represent the mean and S.D. of three independent experiments.