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. 2009 Oct 29;285(1):197–205. doi: 10.1074/jbc.M109.039677

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FIGURE 8. — Processing of ADAMTS9 is decreased in BiP siRNA-transfected cells. A, BiP siRNA suppresses the levels of cellular BiP (left panel) but transfection with BiP siRNA does not affect either the total cellular levels of Pro-Cat (center panel) or furin (right-hand panel). B, expression of BiP siRNA markedly decreases processing (left-hand panel) and cell-surface levels (center panel) of Pro-Cat, but does not affect cell-surface level of furin (right panel). C, quantitation of cell-surface Pro-Cat and furin in BiP siRNA-treated cells is expressed as a percentage of control siRNA-treated cells. Data represent the mean and S.D. of three independent experiments.