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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Pharmacogenomics. 2009 Sep;10(9):1393–1412. doi: 10.2217/pgs.09.93

Table 2.

Genetic association results for SNPs in the bronchodilator response Bayesian network.

SNP CHR BP Gene Minor
allele
Observed genotypes Allelic OR Allelic
p-value
Genotypic
p-value
Bayes
Factor
Cases* Controls*
rs880028 7 50537630 DDC 3 11/36/66 2/74/119 1.38 0.10 0.0011 18.95
rs163688 12 61378399 PPM1H 4 13/39/61 7/50/138 2.06 0.00028 0.0025 8.56
rs6711781 2 218727362 IL8RA 3 5/17/91 0/42/153 1.12 0.66 0.0060 5.90
rs7971621 12 62546881 SRGAP1 3 0/18/95 1/12/182 2.32 0.018 0.016 4.45
rs10052709 5 158693055 IL12B 3 4/16/93 1/50/144 0.77 0.32 0.011 3.94
rs4791036 17 62227597 PRKCA 2 1/32/80 0/32/163 1.98 0.0082 0.017 3.21
rs1110904 12 123549569 NCOR2 4 7/29/77 5/81/109 0.77 0.21 0.010 3.09
rs11172796 12 57565927 LRIG3 4 0/27/86 1/24/170 1.90 0.024 0.024 2.50
rs10879312 12 70361002 TMEM19 4 1/29/83 0/29/166 1.98 0.011 0.025 2.32
rs9468 17 41457408 MAPT 2 6/54/53 13/60/122 1.46 0.047 0.012 1.93
rs7302672 12 62512629 LOC341315 3 7/25/81 5/70/120 0.81 0.32 0.019 1.65
rs4963519 12 6801913 GPR162 4 4/29/80 0/45/150 1.50 0.089 0.024 1.46
rs1493193 12 50192616 LOC283400 2 0/16/97 0/15/180 1.91 0.077 NA 1.07
rs7310083 12 68347053 VMD2L3 4 1/12/100 0/27/168 0.89 0.73 0.31 0.23
CL11302 17 43186946 TBX21 4 3/16/94 1/27/167 1.34 0.32 0.27 0.20

The Bayes Factor column contains Bayes factors that indicate how many times more likely it is that bronchodilator response is dependent on, rather than independent of, a SNP. It is the most consistent with the genotypic model p-values because it is also based on the genotype distribution of each SNP.

*

Shows homozygous minor/heterozygous/homozygous major allele genotype counts.

No NCBI ID available for this marker.

BP: Base pair; CHR: Chromosome; OR: Odds ratio.