Table 2.
SNP | CHR | BP | Gene | Minor allele |
Observed genotypes | Allelic OR | Allelic p-value |
Genotypic p-value |
Bayes Factor |
|
---|---|---|---|---|---|---|---|---|---|---|
Cases* | Controls* | |||||||||
rs880028 | 7 | 50537630 | DDC | 3 | 11/36/66 | 2/74/119 | 1.38 | 0.10 | 0.0011 | 18.95 |
rs163688 | 12 | 61378399 | PPM1H | 4 | 13/39/61 | 7/50/138 | 2.06 | 0.00028 | 0.0025 | 8.56 |
rs6711781 | 2 | 218727362 | IL8RA | 3 | 5/17/91 | 0/42/153 | 1.12 | 0.66 | 0.0060 | 5.90 |
rs7971621 | 12 | 62546881 | SRGAP1 | 3 | 0/18/95 | 1/12/182 | 2.32 | 0.018 | 0.016 | 4.45 |
rs10052709 | 5 | 158693055 | IL12B | 3 | 4/16/93 | 1/50/144 | 0.77 | 0.32 | 0.011 | 3.94 |
rs4791036 | 17 | 62227597 | PRKCA | 2 | 1/32/80 | 0/32/163 | 1.98 | 0.0082 | 0.017 | 3.21 |
rs1110904 | 12 | 123549569 | NCOR2 | 4 | 7/29/77 | 5/81/109 | 0.77 | 0.21 | 0.010 | 3.09 |
rs11172796 | 12 | 57565927 | LRIG3 | 4 | 0/27/86 | 1/24/170 | 1.90 | 0.024 | 0.024 | 2.50 |
rs10879312 | 12 | 70361002 | TMEM19 | 4 | 1/29/83 | 0/29/166 | 1.98 | 0.011 | 0.025 | 2.32 |
rs9468 | 17 | 41457408 | MAPT | 2 | 6/54/53 | 13/60/122 | 1.46 | 0.047 | 0.012 | 1.93 |
rs7302672 | 12 | 62512629 | LOC341315 | 3 | 7/25/81 | 5/70/120 | 0.81 | 0.32 | 0.019 | 1.65 |
rs4963519 | 12 | 6801913 | GPR162 | 4 | 4/29/80 | 0/45/150 | 1.50 | 0.089 | 0.024 | 1.46 |
rs1493193 | 12 | 50192616 | LOC283400 | 2 | 0/16/97 | 0/15/180 | 1.91 | 0.077 | NA | 1.07 |
rs7310083 | 12 | 68347053 | VMD2L3 | 4 | 1/12/100 | 0/27/168 | 0.89 | 0.73 | 0.31 | 0.23 |
CL11302‡ | 17 | 43186946 | TBX21 | 4 | 3/16/94 | 1/27/167 | 1.34 | 0.32 | 0.27 | 0.20 |
The Bayes Factor column contains Bayes factors that indicate how many times more likely it is that bronchodilator response is dependent on, rather than independent of, a SNP. It is the most consistent with the genotypic model p-values because it is also based on the genotype distribution of each SNP.
Shows homozygous minor/heterozygous/homozygous major allele genotype counts.
No NCBI ID available for this marker.
BP: Base pair; CHR: Chromosome; OR: Odds ratio.