Table 2.
Baseline characteristics of the sample without heart failure before listing for kidney transplantation*.
| Baseline Characteristics | Candidates Without HF before Listing (N=21,120) | Underweight (BMI <18.5) (N=811) | Normal weight (BMI 18.5 to<25) (N=8,596) | Overweight (BMI 25 to <30) (N=6,714) | Obese (BMI 30 to <35) (N=3,393) | Morbidly Obese (BMI ≥35) (N=1,606) |
|---|---|---|---|---|---|---|
| n (%) | ||||||
| Age at listing (years) | § | |||||
| 18–30 | 2,973 (14.1) | 265 (32.7) | 1,526 (17.8) | 644 (9.6) | 315 (9.3) | 223 (13.9) |
| 31–45 | 6,884 (32.6) | 283 (34.9) | 3,031 (35.3) | 1,991 (29.7) | 1,033 (30.5) | 546 (34.0) |
| 46–60 | 7,744 (36.7) | 198 (24.4) | 2,804 (32.6) | 2,688 (40.0) | 1,381 (40.7) | 673 (41.9) |
| > 60 | 3,519 (16.7) | 65 (8.0) | 1,235 (14.4) | 1,391 (20.7) | 664 (19.6) | 164 (10.2) |
| Female gender | 8,827 (41.8) § | 512 (63.1) | 3,474 (40.4) | 2,378 (35.4) | 1,568 (46.2) | 895 (55.7) |
| Race | § | |||||
| Black | 7,648 (36.2) | 209 (25.8) | 2,792 (32.5) | 2,497 (37.2) | 1,411 (41.6) | 739 (46.0) |
| White | 11,873 (56.2) | 490 (60.4) | 5,006 (58.2) | 3,801 (56.6) | 1,780 (52.5) | 796 (49.6) |
| Other | 1,599 (7.6) | 112 (13.8) | 798 (9.3) | 416 (6.2) | 202 (6.0) | 71 (4.4) |
| Hispanic ethnicity | 3,776 (17.9) § | 130 (16.0) | 1,537 (17.9) | 1,336 (19.9) | 562 (16.6) | 211 (13.1) |
| Cause of ESRD | § | |||||
| Diabetes | 4,971 (23.5) | 99 (12.2) | 1,639 (19.1) | 1,751 (26.1) | 1,009 (29.7) | 474 (29.5) |
| Hypertension | 5,528 (26.2) | 150 (18.5) | 2,175 (25.3) | 1,858 (27.7) | 925 (27.3) | 420 (26.2) |
| Glomerulonephritis | 5,399 (25.6) | 257 (31.7) | 2,351 (27.4) | 1,630 (24.3) | 766 (22.6) | 395 (24.6) |
| Other | 5,221 (24.7) | 305 (37.6) | 2,431 (28.3) | 1,475 (22.0) | 693 (20.4) | 317 (19.7) |
| Duration of dialysis prior to listing | § | |||||
| Not on dialysis | 7,665 (36.3) | 249 (30.7) | 2,800 (32.6) | 2,495 (37.2) | 1,376 (40.6) | 745 (46.4) |
| 1–12 months | 590 (2.8) | 18 (2.2) | 265 (3.1) | 192 (2.9) | 89 (2.6) | 26 (1.6) |
| 13–24 months | 4,457 (21.1) | 119 (14.7) | 1,764 (20.5) | 1,503 (22.4) | 784 (23.1) | 287 (17.9) |
| ≥25 months | 8,238 (39.0) | 412 (50.8) | 3,682 (42.8) | 2,478 (36.9) | 1,130 (33.3) | 536 (33.4) |
| Unreported | 170 (0.8) | 13 (1.6) | 85 (1.0) | 46 (0.7) | 14 (0.4) | 12 (0.8) |
| Dialysis modality at listing | ||||||
| Peritoneal | 1,772 (8.4) | 77 (9.5) | 712 (8.3) | 586 (8.7) | 290 (8.6) | 107 (6.7) |
| Hemodialysis, none or unreported | 19,348 (91.2) | 734 (90.5) | 7,884 (91.7) | 6,128 (91.3) | 3103 (91.5) | 1,499 (93.3) |
| Comorbidities | ||||||
| Coronary disease or myocardial infarction | 425 (2.0) † | 4 (0.5) | 120 (1.4) | 177 (2.6) | 90 (2.7) | 34 (2.1) |
| Cerebrovascular disease | 467 (2.2) | 19 (2.3) | 197 (2.3) | 161 (2.4) | 62 (1.8) | 28 (1.7) |
| Peripheral vascular disease | 616 (2.9) ‡ | 12 (1.5) | 241 (2.8) | 238 (3.5) | 83 (2.5) | 42 (2.6) |
| Tobacco use | 391 (1.8) ‡ | 15 (1.9) | 187 (2.2) | 122 (1.8) | 53 (1.6) | 14 (0.9) |
| Alcohol dependence | 86 (0.4) ‡ | 1 (0.1) | 46 (0.5) | 31 (0.5) | 7 (0.2) | 1 (0.1) |
| Listing year | § | |||||
| 1995–1998 | 8,154 (38.6) | 389 (48.0) | 3,638 (42.3) | 2,489 (37.1) | 1,112 (32.8) | 526 (32.8) |
| 1999–2001 | 6,217 (29.4) | 226 (27.9) | 2,451 (28.5) | 2,053 (30.6) | 1,005 (29.6) | 482 (30.0) |
| 2002–2004 | 6,749 (32.0) | 196 (24.2) | 2,507 (29.2) | 2,172 (32.4) | 1,276 (37.6) | 598 (37.2) |
BMI, body mass index; ESRD, end-stage renal disease
Percentages reflect proportions within the full sample or BMI category with the indicated demographic or clinical traits (“column percentages”).
*
Restricted to patients with one-year of continuous Medicare coverage before listing and no indication of pre-listing HF.
P-value for Chi-square test of differences in distributions of clinical characteristics according to BMI category:
†
0.02–0.05;
‡
0.002–0.01;
§
<0.001