. Author manuscript; available in PMC: 2010 Jan 11.

Published in final edited form as: Lancet Infect Dis. 2008 Aug;8(8):498–510. doi: 10.1016/S1473-3099(08)70182-8

Table 1. Risk of pulmonary and extra-pulmonary disease in children following infection with MTB.

Adapted from Marais et al. 2004 ²⁹

	Risk of disease following primary infection (%)
Age at infection (years)	Disseminated/TBM^*	Pulmonary TB	No disease	Comments
<1	10-20	30-40	50	High rates of morbidity and mortality
1-2	2-5	10-20	75-80	High rates of morbidity and mortality
2-5	0.5	5	95
5-10	<0.5	2	98	“Safe school years”
>10	<0.5	10-20	80-90	Effusions or adult-type pulmonary disease

TBM = TB meningitis