Interaction between protealysin propeptide and catalytic domain. A, general view. B, omit map contoured at the 3.0σ level in the propeptide region. In A and B, mature portion of N-terminal domain is colored wheat; C-terminal domain, yellow; AYDD-hairpin, pale green; the catalytic zinc ion is shown as an orange sphere. Propeptide is colored blue except for the PPL motif, which is colored magenta. C, interaction of Leu-15 of the PPL motif. Propeptide: α1 is colored blue; α2, green; Leu-15, red. Mature portion is colored yellow orange.