FIGURE 5.

Regulation of AP complement activation by PSP and FH-free PSP. The assays were carried on LPS-coated microtiter plates as described under “Experimental Procedures.” Complement activity is presented as percent of the control level, which was measured as complement activity without the addition of FH-free PSP and PSP. Similar results were obtained from at least three separate experiments. Each value is the mean ± S.D. from triplicate experiments. *, p < 0.05, FH-free PSP was significant compared with PSP. FH-free PSP (open circles) and PSP (filled circles) containing FH.