Table 2.

5-HT-induced changes in cell membrane properties

			Changes in Membrane Properties
	Control		Mean
	Total	EGFP+	Total	EGFP+	↑Em Total	↓Em Total
n	14	11	14	11	7	7
Em, mV	−72.3 ± 8	−72.9 ± 8	−1.3 ± 7	−0.8 ± 5	4.5 ± 3*	−7.1 ± 3*
Ith, pA	107.1 ± 61	118.2 ± 64	−3.6 ± 31	−4.5 ± 35	−7.1 ± 34	0.0 ± 29
Rin, MΩ	347.8 ± 111	342.5 ± 123	64.3 ± 90*	71.5 ± 99*	70.6 ± 54*	58.0 ± 121
Vth, mV	−39.6 ± 10	−39.7 ± 11	−5.1 ± 6*	−3.4 ± 4†	−2.4 ± 4†	−8.3 ± 6†
AP height, mV	43.5 ± 13	39.2 ± 11	−1.7 ± 11	−3.4 ± 11	−2.5 ± 13	−0.7 ± 9
AP width, ms	3.8 ± 1	3.9 ± 1	0.6 ± 1†	0.6 ± 1†	0.4 ± 1	0.7 ± 1†
AHP depth, mV	16.4 ± 8	15.8 ± 8	−1.9 ± 3†	−1.7 ± 3†	−1.5 ± 4	−2.4 ± 2†
AHP 1/2 decay, ms	52.1 ± 43	46.3 ± 27	−8.7 ± 31	−5.6 ± 21	−17.9 ± 39	2 ± 13
Slope SS, Hz/nA	88.3 ± 37	88.1 ± 39	−11.1 ± 37	−20.6 ± 27	−19.2 ± 29	−3.1 ± 47

↑, depolarization (≥2 mV in average); ↓, hyperpolarization (≤−2 mV in average);

^†, significant difference with P < 0.05 and

^*, P < 0.005 performed by paired two-sample t-test.