Table 6.
Mean effect sizes for neuropsychological measures in patients with bipolar illness in a depressed phase as compared to healthy controls. Measures are organized by neurocognitive domain.
| Measure | K | N (patient/control) |
d | 95% CI | Z | p | Qw | p | Nfs |
|---|---|---|---|---|---|---|---|---|---|
| Attention | |||||||||
| Trails A | 3 | 69/89 | .80 | .46/1.13 | 4.64 | <.0001 | 6.73 | .04 | 9 |
|
Verbal Memory | |||||||||
| R/CVLT Total |
4 | 81/109 | 1.20 | .88/1.53 | 7.23 | <.0001 | 5.85 | .12 | 20 |
| Language | |||||||||
| FAS | 5 | 96/124 | .93 | .65/1.22 | 6.47 | <.0001 | 1.77 | .78 | 18 |
|
Executive- Functioning | |||||||||
| Trails B | 3 | 69/89 | .64 | .3/.97 | 3.77 | .0002 | 4.27 | .19 | 7 |
Note: CVLT=California Verbal Learning Test, FAS=Controlled Oral Word Association Test, RAVLT=Rey Auditory Verbal Learning Test. k, number of studies; N, number of participants; ES, weighted effect-size between-groups; 95% CI, 95% confidence interval; Z significance statistic between the groups, Qw within-group homogeneity statistic, Nfs, indicates the number of null findings that would need to be found to reduce the mean effect size to .20.