Figure 3.

Primary structure and sequence alignment of mouse Oc90 and PLA2L (human OC90) with Xenopus laevis OC22. (Upper) line diagram of the OC90 ORF. SP, putative signal peptide; N-term., leader domain; PLA₂-D1 and PLA₂-D2, regions of homology to PLA₂ domains; bridge, region linking the two PLA₂ domains; C-term, carboxyl-terminal domain. (Lower) sequence alignment between mouse and human OC90 and Xenopus laevis OC22 showing alignment of OC22 with both PLA₂ domains of OC90. Residues conserved between all three sequences are shaded. Conserved cysteine residues are marked with a solid bar. Cysteine residues present in mammalian OC90 but not amphibian OC22 are marked with an arrowhead.