Table 3:
Conditions currently under surveillance by national paediatric surveillance units and studies that requested biological specimens at January 1999
| Condition | Unit performing surveillance | |
|---|---|---|
| Current studies | Specimens requested | |
| Acute flaccid paralysis | APSU, CPSP, NSCK, NZPSU, PNGPSU, SPSU | APSU, CPSP, NZPSU, PNGPSU, SPSU |
| Aseptic meningitis following measles, mumps, rubella vaccine | ESPED | |
| Chronic inflammatory bowel disease* | BPSU | |
| Celiac disease | LPSU, NSCK | LPSU |
| Congenital adrenal hyperplasia | NSCK | |
| Congenital brachial palsy | BPSU | |
| Congenital heart disease | MPSU | |
| Congenital hypothyroidism | PNGPSU | |
| Congenital rubella | APSU, BPSU, CPSP, NZPSU, SPSU | CPSP, SPSU |
| Cystic fibrosis | LPSU | |
| Duchenne muscular dystrophy | MPSU | |
| Encephalitis in children three to 36 months of age | BPSU | BPSU |
| Fatal or near fatal asthma | MPSU | |
| Group B streptoccal infection | NSCK | |
| Hemolytic uremic syndrome | APSU, BPSU†, ESPED, NZPSU, SPSU | APSU, BPSU, NZPSU |
| Vitamin K deficiency bleeding (including hemorrhagic disease of the newborn) | APSU, CPSP, ESPED, NZPSU, SPSU | CPSP, SPSU |
| Hirschsprung disease | APSU | |
| HIV/AIDS with or without perinatal exposure to HIV | APSU, BPSU, LPSU, MPSU, NSCK, NZPSU, PNGPSU | BPSU, LPSU |
| Hospitalized pertussis | ESPED, NSCK | |
| Idiopathic thrombocytopenia | ESPED | |
| Insulin-dependent diabetes mellitus | ESPED, LPSU, NSCK, PNGPSU, NZPSU | LPSU |
| Invasive Haemophilus influenzae infection | APSU, BPSU, ESPED | APSU, BPSU |
| Ischemic stroke in infants | ESPED | |
| Leukemia | LPSU | LPSU |
| Lues congenita | LPSU | LPSU |
| Multiple sclerosis in infants | ESPED | |
| Neonatal fungal septicemia | ESPED | |
| Neonatal herpes simplex virus infection | APSU, NZPSU | |
| Neonatal meningitis | MPSU | |
| Neural tube defects | NSCK | |
| Neurological endemic cretinism | PNGPSU | |
| Organocidopathia and fatty acid oxidation defects | ESPED | |
| Paediatric malignancies‡ | PNGPSU | |
| Pneumoccoccal sepsis and/or meningitis | ESPED | ESPED |
| Prader-Willi syndrome | APSU | |
| Primary immunodeficiency disorders§ | APSU | |
| Progredient subacute neurological diseases | LPSU | LPSU |
| Progressive intellectual and neurological deterioration (including Creutzfeld-Jakob disease) | BPSU, CPSP | CPSP |
| Renal tubular acidosis | PNGPSU | |
| Retinopathy of prematurity (stage III and beyond) | NZPSU | |
| Reye syndrome | BPSU | |
| Rotavirus infection | NSCK | |
| Severe combined immunodeficiency | APSU | |
| Subacute sclerosing panencephalitis | APSU, BPSU, CPSP, PNGPSU | CPSP, PNGPSU |
| Subdural hematoma or effusion (in children younger than two years of age) | BPSU, NZPSU | |
| Transient myeloproliferative syndrome in newborns with Down syndrome | ESPED | |
| Venous thromboembolic complaints | NSCK | |
Ulcerative colitis, Crohn’s disease and intermediate colitis;
Previously studied by the British Paediatric Surveillance Unit (BPSU) from 1986 to 1989;
Wilms tumour, Burkitt lymphoma, leukemia, neuroblastoma, lymphoma (non-Burkitt), other;
Predominantly antibody defects (eg, X-linked agammaglobulinemia, immunogloblulin A deficiency, immunogloblulin G subclass deficiency), combined immunodeficiencies (eg, severe combined immunodeficiency, common variable immunodeficiency), immunodeficiencies with other major defects (eg, Wiscott-Aldrich syndrome, Di George syndrome, ataxia telangiectasia), complement deficiencies, including C1 esterase inhibitor deficiency (eg, hereditary angioneurotic edema), defects of phagocytic function (eg, chronic granulomatous disease, leukocyte-adhesion deficiency, Schwachman syndrome) and other. AIDS Acquired immunodeficiency syndrome; APSU Australian Paediatric Surveillance Unit; CPSP Canadian Paediatric Surveillance Program; ESPED Erhebungseinheit fur Seltene Padiatrische Erkrankungen in Deutschland; HIV Human immunodeficiency virus; LPSU Latvian Paediatric Surveillance Unit; MPSU Malaysian Paediatric Surveillance Unit; NSCK Nederlands Signalerings-Centrum Kindergeneeskunde; NZPSU New Zealand Paediatric Surveillance Unit; PNGPSU Papua New Guinea Paediatric Surveillance Unit; SPSU Swiss Paediatric Surveillance Unit