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. 2009 Dec 21;4:68. doi: 10.1186/1748-717X-4-68

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Copyright ©2009 Guckenberger et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Patient # 6: a) planning CT; b) follow-up CT at the end of treatment; c) difference image between planning CT and follow-up CT; d) deformed follow-up CT using all target and organs-at risk meshes; e) deformed follow-up CT using target, lung and spinal cord; f) difference image between planning CT and deformed follow-up CT based on all target organs-at risk meshes. The contours of the macroscopic primary tumor in the planning CT and the follow-up CT are shown in red. Note the distortion of the vertebral body and the trachea without using meshes of these organs for deformable registration in e).