Table 5.
Associations of SRC-3 haplotypes
| Haplotypesa | Cases (%) | Controls (%) | OR | 95% CI | P |
|---|---|---|---|---|---|
| CGA | 1847 (77.0) | 2199 (75.0) | 1 | ||
| CCA | 227 (9.5) | 298 (10.1) | 0.91 | 0.75-1.09 | 0.2963 |
| CGG | 205 (8.5) | 267 (9.1) | 0.91 | 0.75-1.11 | 0.3597 |
| TGA | 119 (4.9) | 162 (5.5) | 0.87 | 0.68-1.12 | 0.2824 |
| CCG | 0 (0.0) | 8 (0.3) | 0.07 | 0.004-1.21 | 0.0096 |
| TCG | 2 (0.1) | 1 (0.0) | 2.38 | 0.22-26.28 | 0.4651 |
| TGG | 0 (0.0) | 1 (0.0) | 0.39 | 0.02-9.74 | 0.3659 |
a haplotypes representing the alleles of C218R, Q586H and T960T compared with wildtype. Haplotype frequencies of SRC-3 polymorphisms C218R, Q586H and T960T in the German study population compared with the, odds ratios (OR) with 95% confidence intervals (95% CI) and P-values.