Figure 1.
Oxytocin induces a change in [Ca2+]i flux in post-pubertal hypothalamic astrocytes. Calcium imaging of astrocytes stimulated with oxytocin at 1 nM, 10 nM, and 100 nM all induced a statistically greater [Ca2+]i flux (ΔF Ca2+ = 330 ± 17 RFU, n=28; ΔF Ca2+ = 331 ± 22 RFU, n=18; and ΔF Ca2+ = 347 ± 13 RFU, n=27, respectively) than control (ΔF Ca2+ = 137 ± 5 RFU, n=14, P < 0.001). Increasing the oxytocin exposure from 1 nM to 100 nM did not significantly increase the [Ca2+]i response. * Significantly different (P < 0.001, one-way ANOVA with Student-Newman-Keuls post hoc test).