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. Author manuscript; available in PMC: 2010 Jan 11.
Published in final edited form as: Nat Genet. 2009 Dec;41(12):1341–1344. doi: 10.1038/ng.490

Figure 1.

Figure 1

(a) Initial screen for association of acute GVHD with donor-recipient mismatch for common gene deletions, in Cohort A. Six common gene-deletion polymorphisms were screened by typing in donors and recipients; data represent association of donor-recipient mismatch (donor −, recipient +) with the development of GVHD after transplantation. Odds ratios and 95% confidence intervals are shown. (b) Analysis in additional patient cohorts of the association of donor-recipient mismatch at UGT2B17 with acute GVHD. (c) Association of UGT2B17 deletion in donor and recipient with GVHD risk. The group of transplants in which both donor and patient were UGT2B17-positive is used as the reference group for analysis. Odds ratios and confidence intervals were calculated using the Cochran-Mantel-Haenszel test to combine data from the 1,345 donor-recipient pairs from Cohorts A, B, and C.