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. Author manuscript; available in PMC: 2010 Jan 11.
Published in final edited form as: Biochemistry. 2008 Aug 22;47(37):9728–9737. doi: 10.1021/bi8006753

Figure 5.

Figure 5

Ribbon representation of the ecTrxR NADPH binding domain (cyan) (PDB code 1TDF) and taTrxR “NADPH binding domain” (yellow). (A) ecTrxR with NADPH binding amino acids, H175, R176, R177, and R181, represented in stick form. (B) taTrxR structure with corresponding structurally aligned amino acids, E185, Y186, M187 and M191 represented in stick form with modeled NADPH. (C) Superposition of ecTrxR and taTrxR NADPH binding domains with NADPH from ecTrxR structure (D) Sequence alignment of the NADPH binding domain regions.