Table 2.
Predicting first onset of FS conditions during T2–T4 from baseline FS and SUB conditions (not adjusted for comorbidity)
| Diagnoses at T1 | Met diagnostic criteria for Full syndrome for first time at T2, T3, or T4 | |||||
|---|---|---|---|---|---|---|
| Depression (N=1198) | Bipolar (N=1493) | Anxiety (N=1382) | Alcohol (N=1435) | Substance (N=1417) | Conduct/ASPD (N=1465) | |
| FS-depression | N/A |
3.6% HR =4.7 (1.1–19.9) |
21.1% HR = 2.1 (1.4–3.2) |
31.1% HR = 1.6 (1.3–2.2) |
17.4% |
2.1% HR = 2.9 (1.1–7.5) |
| SUB-MDD |
35.3% HR =1.6 (1.2–2.0) |
0.8% | 9.2% | 20.8% | 10.6% | 1.6% |
| Non-MDD | 19.3% | 0.5% | 6.6% | 17.9% | 11.0% | 1.5% |
| FS-Bipolar | 12.5% | N/A | 25.0% | 18.2% | 30.0% | 0% |
| SUB-Bipolar |
51.4% HR =2.1 (1.3–3.4) |
3.4% |
25.0% HR = 3.0 (1.5–6.0) |
34.5% | 13.0% | 1.8% |
| Non-Bipolar | 23.8% | 1.1% | 9.3% | 20.7% | 11.9% | 1.6% |
| FS-Anxiety |
55.6% HR=2.3 (1.6–3.2) |
2.5% | N/A | 29.5% | 16.2% | 1.7% |
| SUB-Anxiety | 28.2% | 1.2% |
14.6% HR=1.5 (1.0–2.3) |
21.4% | 14.7% | 1.7% |
| Non-Anxiety | 21.9% | 1.1% | 8.8% | 20.3% | 11.1% | 1.6% |
| FS-Alcohol | 41.7% HR = 1.6 (0.9–2.9)+ |
4.3% HR = 3.6 (1.0–13.3)+ |
16.9% HR= 1.8 (0.9–3.5)+ |
N/A |
35.7% HR =3.6 (1.8–7.5) |
10.9% HR=12.0 (4.5–32.2) |
| SUB-Alcohol | 30.2% | 1.5% | 11.4% |
36.4% HR = 2.0 (1.5–2.7) |
21.8% HR = 2.0 (1.4%3.0) |
2.1% |
| Non-Alcohol | 23.3% | 1.0% | 9.2% | 18.8% | 10.1% | 1.1% |
| FS-Substance | 35.0% |
4.7% HR = 4.3 (1.3–14.3) |
18.4% HR = 2.0 (1.1–3.5) |
45.7% HR = 2.2 (1.4–3.4) |
N/A |
8.3% HR = 7.8(3.0–20.0) |
| SUB-Substance | 25.9% | 3.5% HR = 3.3 (0.9–12.0)+ |
15.2% HR =1.7 (1.0–3.2)+ |
43.6% HR = 2.5 (1.7–3.7) |
37.9% HR =4.1 (2.7–6.3) |
3.8% |
| Non-Substance | 24.1% | 0.8% | 9.0% | 19.0% | 10.4% | 1.1% |
| FS-Conduct | 27.3% | 2.5% | 8.1% |
68.0% HR =4.4 (2.5–7.5) |
62.5% HR =7.9 (4.4–14.1) |
N/A |
| SUB-Conduct | 33.3% |
6.5% HR = 6.5 (2.1–19.6) |
17.3% HR = 1.9 (1.0–3.3) |
43.4% R = 2.4 (1.7–3.4) |
28.4% HR =2.6 (1.6–4.1) |
7.4% HR = 6.7 (2.6–17.2) |
| Non-conduct | 24.1% | 0.8% | 9.4% | 18.9% | 10.2% | 1.2% |
| FS-ADHD |
40.6% HR =2.1 (1.2–3.8) |
2.5% | 14.7% | 38.9% HR= 1.6 (0.9–2.8)+ |
28.6% HR = 2.5 (1.3–4.7) |
2.9% |
| SUB-ADHD | 33.3% | 2.4% | 13.7% |
36.3% HR = 1.6 (1.1–2.5) |
29.6% HR = 3.0 (1.9–4.8) |
6.5% HR = 4.4(1.5–12.6) |
| Non-ADHD | 23.7% | 1.1% | 9.5% | 19.8% | 10.5% | 1.3% |
SUB=Subthreshold. FS=full syndrome. Percentages are observed incidence of diagnosis at T2–T4. Comparison group for Hazard ratios (HR) is non-SUB, non-FS. 95% confidence intervals are presented next to HR. HR are adjusted for sex. HR that are bolded are significant at p<.05. Plus-sign = .05< p<.10