Table 3.
General linear model estimates of factors with putative impact on S-homocysteine concentration (dependent variable)
Independent variable | Coefficient | 95% confidence interval (min–max) | P |
---|---|---|---|
Male gender | 1.57 | 0.65–2.49 | 0.001 |
Age | 0.08 | 0.0–0.13 | 0.001 |
BMI | −0.03 | −0.17–0.10 | 0.62 |
Diabetes mellitus | 2.52 | −0.42–5.46 | 0.09 |
Hypothyreosis | 0.84 | −2.92–4.60 | 0.66 |
S-cystatin C | 2.71 | 1.26–4.15 | <0.001 |
S-vitamin B12 | −0.01 | −0.01–0.00 | <0.001 |
S-folate | −0.16 | −0.24–−0.08 | <0.001 |
MTHFR 677 TT genotype | 1.645 | 0.27–3.02 | 0.02 |
Atrophy of the gastric corpus mucosa | 4.62 | 2.00–7.24 | 0.001 |
Atrophy of the duodenal mucosa (Alexander grade III–IV) | 2.50 | −0.75–5.76 | 0.13 |