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. 2008 Dec 23;80(4):771–780. doi: 10.1095/biolreprod.108.072843

FIG. 4.

FIG. 4.

SB203580 confers resistance to heat-induced germ cell apoptosis by suppressing NOS2 induction, BCL2 phosphorylation, and cytosolic translocation of cytochrome c (CYCS). Representative Western blots of testicular lysates from control, heat, and heat + SB203580-treated rats show effective suppression of NOS2 and BCL2 phosphorylation (pBCL2) (A) and cytosolic translocation of CYCS during heat-induced male germ cell death (B). Data are representative of three to five animals at each treatment group from one of three separate experiments.