A-B. Fasting glucose (A) and insulin (B) in 10-weeks-old CXCR2 −/− and control mice before (chow) and after 7 weeks of high fat diet (HFD)(n=10 mice per group).
C. Body weight in control and CXCR2 −/− mice in chow and high fat diet.
D. Food intake in control and CXCR2 −/− mice.
E-F. Glucose clearance after intraperitoneal injection of insulin (E) or glucose (F) in control and CXCR2 −/− mice under chow or high fat diet. Area under the curve was analyzed (AUC).