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. Author manuscript; available in PMC: 2010 Jan 12.
Published in final edited form as: Toxicol Appl Pharmacol. 2009 Jan 23;236(2):154–165. doi: 10.1016/j.taap.2008.12.028

Fig. 1.

Fig. 1

Effect of Cr(VI) on HeLa cell proliferation. Cell proliferation and intact cell DNA synthesis reactions were performed as described in the Methods. (A) The effects of sodium dichromate on HeLa cell proliferation were measured in cultured cells using the MTT assay following 8, 24 and 48 h of incubation with a range of concentrations of the metal ion. (B) The effects of sodium dichromate on intact cell DNA synthesis were measured by monitoring the incorporation of (3H)-thymidine into cells following 1, 2.5 or 8 h of incubation with a range of concentrations of the metal ion. The values reported were the average of three separate experiments. The degree to which Cr(VI) ion inhibits cell proliferation and intact cell DNA synthesis was calculated relative to an untreated control group and was reported as a percentage of the control.