Table 3.
The average percentage overlap of chemical markers across all cortical layers (1–6) in mouse frontal cortex (FC), primary somatosensory cortex (S1) and visual cortex (V1)
| I. FC | ||||||
|---|---|---|---|---|---|---|
| SOM | CR | VIP | NPY | PV | ||
| All Layers | SOM | 26.8(294/1098) | 0(0/960) | 9.3(49/526) | 0.1(1/781) | |
| CR | 41.2(294/713) | 29.9(155/519) | 8.5(56/662) | 0(0/432) | ||
| VIP | 0(0/391) | 30.3(155/512) | 10.4(41/394) | 0(0/370) | ||
| NPY | 25.4(49/193) | 12.4(56/452) | 8.4(41/489) | 0.5(2/389) | ||
| PV | 0.1(1/1048) | 0(0/1337) | 0(0/1463) | 0.2(2/1266) | ||
| Layer 1 | SOM | 57.1(4/7) | 0(0/10) | 16.7(1/6) | 0(0/5) | |
| CR | 17.4(4/23) | 5.6(1/18) | 14.3(2/14) | 0(0/24) | ||
| VIP | 0(0/37) | 2.3(1/44) | 2.5(1/40) | 0(0/19) | ||
| NPY | 5.9(1/17) | 5.7(2/35) | 3.1(1/32) | 0(0/31) | ||
| PV | 0(0/3) | 0(0/4) | 0(0/1) | 0(0/0) | ||
| Layer 2/3 | SOM | 81.4(149/183) | 0(0/124) | 11.5(9/78) | 0(0/138) | |
| CR | 41.2(149/362) | 28.6(71/248) | 5.1(16/314) | 0(0/234) | ||
| VIP | 0(0/207) | 26.3(71/270) | 12.9(26/201) | 0(0/208) | ||
| NPY | 12.9(9/70) | 10.2(16/157) | 14.6(26/178) | 0(0/159) | ||
| PV | 0(0/250) | 0(0/326) | 0(0/280) | 0(0/280) | ||
| Layer 4 | SOM | 44(73/166) | 0(0/158) | 2.8(3/107) | 0(0/132) | |
| CR | 41(73/178) | 27.2(37/136) | 4.4(7/159) | 0(0/98) | ||
| VIP | 0(0/41) | 53.6(37/69) | 17.5(10/57) | 0(0/45) | ||
| NPY | 9.7(3/31) | 9.5(7/74) | 14.5(10/69) | 1.7(1/60) | ||
| PV | 0(0/285) | 0(0/334) | 0(0/364) | 0.3(1/329) | ||
| Layer 5 | SOM | 11.5(51/443) | 0(0/148) | 6.5(13/200) | 0.4(1/259) | |
| CR | 51.5(51/99) | 39.5(30/76) | 14.5(16/110) | 0(0/57) | ||
| VIP | 0(0/62) | 42.9(30/70) | 3.8(2/52) | 0(0/49) | ||
| NPY | 33.3(13/39) | 18.4(16/87) | 1.8(2/109) | 1.5(1/66) | ||
| PV | 0.3(1/344) | 0(0/448) | 0(0/563) | 0.2(1/439) | ||
| Layer 6 | SOM | 5.7(17/299) | 0(0/265) | 17(23/135) | 0(0/247) | |
| CR | 33.3(17/51) | 39(16/41) | 23.1(15/65) | 0(0/19) | ||
| VIP | 0(0/44) | 27.1(16/59) | 4.5(2/44) | 0(0/49) | ||
| NPY | 63.9(23/36) | 15.2(15/99) | 2(2/101) | 0(0/73) | ||
| PV | 0(0/166) | 0(0/225) | 0(0/255) | 0(0/218) | ||
| II. S1 | ||||||
|---|---|---|---|---|---|---|
| SOM | CR | VIP | NPY | PV | ||
| All Layers | SOM | 15.1(240/1587) | 0(0/1482) | 6.5(50/770) | 0(0/1220) | |
| CR | 33(240/728) | 32.4(149/460) | 12.3(72/585) | 0(0/290) | ||
| VIP | 0(0/510) | 26.5(149/562) | 11.8(52/441) | 0(0/332) | ||
| NPY | 19.1(50/262) | 11.8(72/609) | 7.7(52/672) | 0.5(3/657) | ||
| PV | 0(0/1975) | 0(0/1883) | 0(0/1264) | 0.1(3/2512) | ||
| Layer 1 | SOM | 90.9(10/11) | 0(0/11) | 0(0/3) | 0(0/3) | |
| CR | 40(10/25) | 0(0/18) | 0(0/13) | 0(0/7) | ||
| VIP | 0(0/16) | 0(0/17) | 21.4(3/14) | 0(0/7) | ||
| NPY | 0(0/4) | 0(0/26) | 13.6(3/22) | 0(0/26) | ||
| PV | 0(0/3) | 0(0/2) | 0(0/0) | 0(0/1) | ||
| Layer 2/3 | SOM | 57.8(129/223) | 0(0/199) | 9.6(11/115) | 0(0/186) | |
| CR | 37.1(129/348) | 28(66/236) | 9.5(27/285) | 0(0/131) | ||
| VIP | 0(0/284) | 21.5(66/307) | 12.2(30/245) | 0(0/152) | ||
| NPY | 10.6(11/104) | 9.9(27/272) | 10.5(30/285) | 1(3/290) | ||
| PV | 0(0/302) | 0(0/255) | 0(0/164) | 0.8(3/385) | ||
| Layer 4 | SOM | 7.1(20/283) | 0(0/206) | 0.7(1/142) | 0(0/216) | |
| CR | 13.7(20/146) | 35.1(27/77) | 7.8(9/115) | 0(0/72) | ||
| VIP | 0(0/79) | 35.5(27/76) | 15.6(12/77) | 0(0/70) | ||
| NPY | 2.2(1/46) | 10(9/90) | 13.5(12/89) | 0(0/70) | ||
| PV | 0(0/587) | 0(0/612) | 0(0/338) | 0(0/797) | ||
| Layer 5 | SOM | 8(47/588) | 0(0/545) | 2.1(6/283) | 0(0/430) | |
| CR | 37.9(47/124) | 38.8(31/80) | 12.6(12/95) | 0(0/59) | ||
| VIP | 0(0/58) | 41.3(31/75) | 9.1(5/55) | 0(0/51) | ||
| NPY | 12.8(6/47) | 14.5(12/83) | 4.9(5/102) | 0(0/102) | ||
| PV | 0(0/634) | 0(0/586) | 0(0/412) | 0(0/821) | ||
| Layer 6 | SOM | 7.1(34/482) | 0(0/521) | 14.1(32/227) | 0(0/385) | |
| CR | 40(34/85) | 51(25/49) | 31.2(24/77) | 0(0/21) | ||
| VIP | 0(0/73) | 28.7(25/87) | 4(2/50) | 0(0/52) | ||
| NPY | 52.5(32/61) | 17.4(24/138) | 1.1(2/174) | 0(0/169) | ||
| PV | 0(0/449) | 0(0/428) | 0(0/350) | 0(0/508) | ||
| III. S1 | ||||||
|---|---|---|---|---|---|---|
| SOM | CR | VIP | NPY | PV | ||
| All Layers | SOM | 27.1(221/814) | 0(0/785) | 5.8(33/569) | 0(0/666) | |
| CR | 34.3(221/645) | 39.7(229/577) | 9.5(66/697) | 0(0/388) | ||
| VIP | 0(0/416) | 47.4(229/483) | 6.2(27/433) | 0(0/307) | ||
| NPY | 21.6(33/153) | 21.9(66/302) | 8.4(27/323) | 0(0/218) | ||
| PV | 0(0/979) | 0(0/973) | 0(0/1072) | 0(0/925) | ||
| Layer 1 | SOM | 75(3/4) | 0(0/8) | 0(0/6) | 0(0/7) | |
| CR | 18.8(3/16) | 18.5(5/27) | 9.5(2/21) | 0(0/10) | ||
| VIP | 0(0/22) | 14.3(5/35) | 0(0/24) | 0(0/16) | ||
| NPY | 0(0/6) | 25(2/8) | 0(0/11) | 0(0/10) | ||
| PV | 0(0/0) | 0(0/0) | 0(0/2) | 0(0/3) | ||
| Layer 2/3 | SOM | 63.2(67/106) | 0(0/104) | 4(2/50) | 0(0/85) | |
| CR | 26.2(67/256) | 45.1(114/253) | 9.4(30/318) | 0(0/163) | ||
| VIP | 0(0/232) | 43.7(114/261) | 8.7(21/241) | 0(0/173) | ||
| NPY | 2.9(2/70) | 20.7(30/145) | 13.2(21/159) | 0(0/108) | ||
| PV | 0(0/106) | 0(0/119) | 0(0/133) | 0(0/119) | ||
| Layer 4 | SOM | 39.5(100/253) | 0(0/252) | 2.1(4/192) | 0(0/240) | |
| CR | 39.2(100/255) | 27.6(58/210) | 6.6(16/244) | 0(0/154) | ||
| VIP | 0(0/78) | 59.8(58/97) | 4.7(4/86) | 0(0/54) | ||
| NPY | 14.3(4/28) | 30.2(16/53) | 7.4(4/54) | 0(0/37) | ||
| PV | 0(0/368) | 0(0/349) | 0(0/333) | 0(0/358) | ||
| Layer 5 | SOM | 13.6(44/324) | 0(0/275) | 5.2(11/213) | 0(0/214) | |
| CR | 54.3(44/81) | 50(26/52) | 9.7(7/72) | 0(0/41) | ||
| VIP | 0(0/51) | 56.5(26/46) | 2.8(1/36) | 0(0/39) | ||
| NPY | 52.4(11/21) | 17.5(7/40) | 1.9(1/54) | 0(0/30) | ||
| PV | 0(0/277) | 0(0/340) | 0(0/375) | 0(0/286) | ||
| Layer 6 | SOM | 5.5(7/127) | 0(0/146) | 14.8(16/108) | 0(0/120) | |
| CR | 18.9(7/37) | 74.3(26/35) | 26.2(11/42) | 0(0/20) | ||
| VIP | 0(0/33) | 59.1(26/44) | 2.2(1/46) | 0(0/25) | ||
| NPY | 57.1(16/28) | 19.6(11/56) | 2.2(1/45) | 0(0/33) | ||
| PV | 0(0/228) | 0(0/165) | 0(0/229) | 0(0/159) | ||
Note that the overlap percentage indicates % of the marker populations in rows positive for the markers in columns. The numbers inside the parenthesis () indicate the numbers of cells measured to calculate the percentage.