TABLE 2.
DISTRIBUTION OF DAY 80 PULMONARY FUNCTION TEST PARAMETERS, LUNG FUNCTION SCORE AND LUNG FUNCTION SCORE CATEGORIES
| Lung function parameters; N (%) | |||||
|---|---|---|---|---|---|
| PFT parameter | ≥ 80% | 70–79% | 60–69% | < 60% | Mean (% predicted) (SD) |
| FEV1 | 1566 (73) | 347 (16) | 155 (7) | 90 (4) | 88 (15) |
| FVC | 1732 (80) | 259 (12) | 112 (5) | 55 (3) | 93 (16) |
| TLC* | 1779 (88) | 174 (9) | 49 (2) | 17 (<1) | 97 (15) |
| DLCO† | 1035 (51) | 424 (21) | 329 (16) | 224 (11) | 81 (18) |
| FEV1/FVC | ≥ 0.7 | < 0.7 | |||
| 1908 (88) | 250 (12) | 0.78 (0.07) | |||
| Lung Function Scores and Lung Function Score Categories | |||||
|---|---|---|---|---|---|
| LFS frequency† | N | (%) | LFS category frequency | N | (%) |
| 2 | 896 | (42) | 0 | 896 | (42) |
| 3 | 427 | (20) | |||
| 4 | 289 | (13) | 1 | 898 | (42) |
| 5 | 182 | (8) | |||
| 6 | 93 | (4) | |||
| 7 | 59 | (3) | 2 | 198 | (9) |
| 8 | 30 | (1) | |||
| 9 | 16 | (1) | |||
| 10–12 | 20 | (1) | 3 | 20 | (1) |
*
TLC only available for 2019 (94%) patients
†
DLCO and LFS only available for 2012 (93%) patients
LFS categories were calculated as follows: Category 0 = LFS 2, category 1 = LFS 3–5, category 2 = LFS 6–9, category 3 = LFS 10–12