Table 2.
Nucleotide Excision Repair in Zebrafish Skin
| |
|
CPDs/mb DNA |
(6-4)PDs/mb DNA |
||||
|---|---|---|---|---|---|---|---|
| Time of repair | Mean (n = 5) | SD | Remaining% | Mean (n = 5) | SD | Remaining% | |
| wt | UV | 98.6 | 6.9 | 8.7 | 2.5 | ||
| 0 | 567.2 | 106.7 | 100 | 92.2 | 26.4 | 100 | |
| 3 | 766.4 | 100.9 | 135 | 115.1 | 22.6 | 125 | |
| 6 | 692.3 | 109.3 | 122 | 89.7 | 21.9 | 97 | |
| 24 | 133.0 | 18.4 | 23 | 10.8 | 2.9 | 12 | |
| p53 | UV | 99.6 | 16.4 | 8.8 | 3.0 | ||
| 0 | 767.6 | 206.6 | 100 | 130.3 | 33.6 | 100 | |
| 3 | 783.7 | 127.1 | 102 | 123.2 | 18.4 | 95 | |
| 6 | 709.5 | 141.1 | 92 | 105.4 | 24.6 | 81 | |
| 24 | 570.3 | 130.8 | 74 | 83.0 | 22.4 | 64 | |
CPD, cyclobutane pyrimidine dimers; SD, standard deviation; UV, ultraviolet; wt, wild type.