Table 1. Demographic and mutation data of the patients enrolled in this study.
| Sample ID | Epithelial culture | BRCA | Mutation | Age | Race | Parity | Menopause status | Weight (pounds) | Height (inches) | Body mass index |
|---|---|---|---|---|---|---|---|---|---|---|
| 218 | Breast | B1 | 2800delAA; BRCA1 c.2681_2682del | 45 | C | 2 | Post | 165 | 70 | 23.7 |
| 256 | Breast | B1 | R1835X; BRCA1 c5503C>T (p.R1835X) | 50 | C | 2 | Post | 137 | 62 | 25.1 |
| 288 | Breast | B1 | 185delAG; BRCA1 c.68_69delAG | 70 | C | 2 | Post | 116 | NA | NA |
| 349 | Breast | B1 | 1997insTAGT; BRCA1 c.1878_1879insTAGT | 28 | C | 0 | Pre | 127 | 64 | 22.5 |
| 425 | Breast | B1 | T1194I, BRCA1 c.3581C>T (pT119I)* | 45 | C | 5 | Pre | 126 | 64 | 22.3 |
| 479 | Breast | B1 | R1751X; BRCA1 c.5251C>T (p.R1751X) | 48 | C | 3 | Post | 211 | 64 | 37.4 |
| 182 | Breast | B2 | 6174delT; BRCA2 c.5945delT | 44 | C | 0 | Pre | 115 | 66 | 19.1 |
| 197 | Breast | B2 | 2912delC; BRCA2 c.2683delC | 47 | C | 4 | Pre | 138 | 62 | 25.2 |
| 285 | Breast | B2 | R2394X; BRCA2 c.7181A>T | 37 | AA | 3 | Pre | 234 | 63 | 41.4 |
| 300 | Breast | B2 | UN | 45 | C | 2 | Pre | 131 | 64 | 23.2 |
| 304 | Breast | B2 | K745E; BRCA2 c.2233A>G (p.K745E)* | 61 | AA | 2 | Post | 204 | 64 | 36.1 |
| 308 | Breast | B2 | UN | 51 | C | 0 | Post | NA | NA | NA |
| 158 | Breast | WT | — | 59 | C | 2 | Post | 170 | NA | NA |
| 162 | Breast | WT | — | 74 | C | NA | Post | 130 | NA | NA |
| 161 | Breast | WT | — | 69 | C | 3 | Post | 125 | NA | NA |
| 169 | Breast | WT | — | 49 | C | 3 | Per | NA | NA | NA |
| 187 | Breast | WT | — | 31 | C | 0 | Pre | 161 | 65 | 27.6 |
| 181 | Breast | WT | — | 39 | C | 0 | Post | 102 | NA | NA |
| 166 | Ovary | B1 | IVS16-581del1014; BRCA1-c.4986-581del1014 | 28 | C | 2 | Pre | NA | NA | 18.3 |
| 183 | Ovary | B1 | IVS12-1632del3835; BRCA1-c.4185-1632del3855 | 43 | C | 2 | Pre | NA | NA | NA |
| 193 | Ovary | B1 | IVS16-581del1014; BRCA1-c.4986-581del1014 | 37 | C | 0 | Pre | NA | NA | 20.8 |
| 194 | Ovary | B1 | 1632del5-ter503; BRCA1 c.1513del5 (p.503X) | 43 | C | 2 | Pre | NA | NA | NA |
| 201 | Ovary | B1 | IVS12-1632del3835; BRCA1-c.4185-1632del3855 | 44 | C | 3 | Pre | NA | NA | 29.4 |
| 217 | Ovary | B1 | UN | 46 | C | NA | NA | NA | NA | NA |
| 302 | Ovary | B2 | 9663delGT; BRCA1 c9434_9435del | 44 | C | 3 | Pre | 184 | 66 | 28.2 |
| 206 | Ovary | B2 | 9132delC-ter2975; BRCA2 c.8903delC (p.2975X) | 39 | C | 2 | Pre | 110 | 64 | 18.9 |
| 328 | Ovary | B2 | UN | 38 | C | 3 | Pre | 189 | NA | NA |
| 431 | Ovary | B2 | 6174delT; BRCA2 c.5945delT | 54 | C | 0 | Post | 137 | 64 | 24.3 |
| 470 | Ovary | B2 | UN | 57 | C | 1 | Post | 123 | 60 | 24 |
| 612 | Ovary | B2 | UN | 42 | C | 3 | Pre | 145 | 66 | 23.4 |
| 178 | Ovary | WT | — | 60 | C | 0 | Post | 286 | 65 | 47.6 |
| 211 | Ovary | WT | — | 40 | C | 3 | Pre | 121 | NA | NA |
| 276 | Ovary | WT | — | 38 | C | 4 | Pre | 188 | 65 | 31.3 |
| 207 | Ovary | WT | — | 45 | C | 0 | Post | 130 | 61 | 24.6 |
| 121 | Ovary | WT | — | 33 | C | 0 | Post | 200 | 65 | 33.3 |
| 600 | Ovary | WT | — | 45 | C | 2 | Pre | 155 | 64 | 26.6 |
Abbreviations: WT, individual tested negative for a BRCA1 and BRCA2 alteration; UN, patient self reported prior to surgery but declined to share the specific mutation
*
Missense mutation, unique to Breast Cancer Information Core (http://research.nhgri.nih.gov/bic/index.shtml), segregates with disease, suspected deleterious C, Caucasian; AA, African American
NA, information was not available