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. Author manuscript; available in PMC: 2010 Jan 12.
Published in final edited form as: J Cell Physiol. 2008 Oct;217(1):13–22. doi: 10.1002/jcp.21445

Figure 1. Double transgenic mice with doxycycline-inducible expression of sVEGFR1Fc in the retina.

Figure 1

Double transgenic Tet/IRBP/sVEGFR1Fc or Tet/opsin/sVEGFR1Fc mice were given 2 mg/ml of doxycycline in their drinking water for 2 weeks and then euthanized and retinal homogenates were run in immunoblots using an anti-VEGFR1 antibody. Both Tet/IRBP/VEGFR1Fc and Tet/opsin/VEGFR1Fc mice treated with doxycycline showed bands for sVEGFR1Fc. There was minimal leakiness in the absence of doxycycline. All of the retinas showed similar bands for endogenous murine VEGFR1 indicating that the differences in sVEGFR1Fc are not due to loading differences.