. Author manuscript; available in PMC: 2010 Jan 12.

Published in final edited form as: FASEB J. 2006 Feb 7;20(6):768–769. doi: 10.1096/fj.05-4607fje

Table 3.

Phenylalanine kinetics across the leg in young and older adults in the basal state and during insulin infusion in the femoral artery of one leg

	Young Adults		Older Adults
	Basal	Insulin	Basal	Insulin
	(nmol·min⁻¹·100 ml leg⁻¹)
F_in – Delivery to the leg	221 ± 25	338 ± 65	156 ± 12^†	145 ± 8^†
F_out – Release from the leg	243 ± 29	322 ± 63	171 ± 13^†	149 ± 1^†
F_ma – Transport into muscle free pool	144 ± 35	158 ± 41	113 ± 20	75 ± 11
F_vm – Transport from muscle free pool	164 ± 37	142 ± 38^*	128 ± 21	79 ± 11^*
F_va – Arteriovenous shunting	77 ± 28	180 ± 39^*	43 ± 11^†	70 ± 12^*^†
F_om – Utilization for protein synthesis	40 ± 8	93 ± 21^*	58 ± 8	57 ± 12^†
F_mo – Release from proteolysis	63 ± 13	78 ± 19	73 ± 9	61 ± 14
Rd – Disappearance from the blood	35 ± 8	71 ± 19^*	48 ± 9	40 ± 7^†
Ra – Release in blood from proteolysis	57 ± 13	56 ± 16	63 ± 10	44 ± 9
IC_av – Intracellular availability	225 ± 41	235 ± 57	186 ± 27	136 ± 21^*^†
NB – Net balance across the leg	−22 ± 5	15 ± 4^*	−15 ± 2	−4 ± 2^*^†

P < 0.05 vs. Basal

^†

P < 0.05 vs. Young Adults.