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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Jul 1;1(4):391–404. doi: 10.1002/wnan.40

Table 1.

Recent Studies Elucidating Shape Effects on Polymer Nanoparticle-Mediated Drug Delivery and Therapeutic Imaging Applications

Particle Matrix and Description Size Range Studied Shape Reference
PEG-based Diblock copolymers 22–66 nm × 0.5–8 μm Spheres vs. flexible filaments [66]
Polystyrene 1–10 μm Spheres, oblate or prolate ellipsoids, elliptical discs, rectangular discs, “UFO’s” [62, 63]
Degradable and non-degradable PEG-based hydrogels 100 nm – 5 μm Cubes, cylinders, rods [44–46, 67]
Degradable peptide diacrylates gels vs. Non-degradable PEG-based hydrogels 50–400 nm Squares, triangle, pentagons [68]