(A) Histologic appearance of the cellular xenograft at 7 days post surgery. The cellular xenograft (blue staining) appeared minimally degraded at 7 days post surgery. A dense population of both neutrophils and mononuclear cells were present in the operative site; however, there was minimal invasion of the cells into the cellular xenograft. (B) Histologic appearance of the cellular xenograft at 28 days post surgery. The cellular xenograft was no longer discernable at 28 days and was replaced with dense poorly organized collagenous connective tissue (dark blue staining, bracket), a small amount of adipose tissue (arrows), and a randomly distributed population of mononuclear cells. The red staining tissue bundles at the bottom of the image represent the underlying transversalis muscle (Masson's Trichrome, 200×).