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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Clin Endocrinol (Oxf). 2009 Mar 30;72(1):99–106. doi: 10.1111/j.1365-2265.2009.03599.x

Table 2.

Cognitive Function Test (CFT) Score Characteristics and Multivariate Linear Associations (standardized β-coefficients) of Estrogens with Annualized Change in CFT Scores Over 4 Years.

Cognitive Function Test Mean Baseline Score (SD) Mean Annual Change (SD) Linear association with annualized change in CFT score
Estrone Estradiol Bioavailable Estradiol
β-coeff. p-value β-coeff. p-value β-coeff. p-value
MMSE 27.5 (1.6) .09 (.48) 0.03 .55 0.03 .61 0.05 .37
Trails B 130.2 (59.2) −4.6 (14.2) 0.05 .39 −0.02 .78 0.01 .96
Category fluency 17.5 (4.6) −.30 (1.03) −0.12 .04 −0.04 .50 −0.10 .09

Models are adjusted for age, education and mean CFT score.

Estrogen levels were log-transformed for analyses.