Table 1.
In.[a] | R[b] | IC50[c] [µm] |
In.[a] | R[b] | IC50[c] [µm] |
---|---|---|---|---|---|
P1 | <0.1 | P9 | TCPP(Asp)4 | <10 | |
P2 | <0.1 | C10 | <10 | ||
P3 | <0.1 | C11 | <100 | ||
P4 | <1 | C12 | <100 | ||
P5 | <10 | C13 | – | ||
P6 | – | C14 | – | ||
P7 | – | O15–17 | – | ||
P8 | – | O18 | – |
Inhibitor;
modifying groups;
concentration [µm] that led to more than 50% inhibition of the SCF*–KIT interaction.